研究成果

研究成果

論文発表

■英文

2017年

Matsuo R, Yamaguchi Y, Matsushita T, Hata J, Kiyuna F, Fukuda K, Wakisaka Y, Kuroda J,Ago T, Kitazono T, Kamouchi M

Association Between Onset-to-Door Time and Clinical Outcomes After Ischemic Stroke
Stroke 2017

脳梗塞の発症後来院時間と予後の関連を明らかにしました。超急性期再灌流療法非適応例でも、軽症例でも、来院が早ければ早いほど、予後が良好であることがあきらかとなりました。

Ogata T, Matsuo R, Kiyuna F, Hata J, Ago T, Tsuboi Y, Kitazono T, Kamouchi M; FSR Investigators.
Left Atrial Size and Long-Term Risk of Recurrent Stroke After Acute Ischemic Stroke in Patients With Nonvalvular Atrial Fibrillation.
J Am Heart Assoc. 2017;6(8). e006402.

Wakisaka Y, Matsuo R, Hata J, Kuroda J, Kitazono T, Kamouchi M, Ago T, on behalf of the Fukuoka Stroke Registry Investigators.
Adverse Influence of Pre-Stroke Dementia on Short-Term Functional Outcomes in Patients with Acute Ischemic Stroke: The Fukuoka Stroke Registry.
Cerebrovasc Dis 2017;43:82–89

2016年

Matsuo R, Michikawa T, Ueda K, Ago T, Nitta H, Kitazono T, Kamouchi M; Fukuoka Stroke Registry Investigators.
Short-Term Exposure to Fine Particulate Matter and Risk of Ischemic Stroke.
Stroke 2016; Nov 3
脳梗塞発症とPM2.5曝露との関連を明らかにしました。

Ishikawa H, Wakisaka Y, Matsuo R, Makihara N, Hata J, Kuroda J, Ago T, Kitayama J, Nakane H, Kamouchi M, Kitazono T; Fukuoka Stroke Registry Investigators.
Influence of Statin Pretreatment on Initial Neurological Severity and Short-Term Functional Outcome in Acute Ischemic Stroke Patients: The Fukuoka Stroke Registry.
Cerebrovasc Dis. 2016 Jul 5;42(5-6):395-403

Matsuo R, Ago T, Hata J, Wakisaka Y, Kuroda J, Kuwashiro T, Kitazono T, Kamouchi M; Fukuoka Stroke Registry Investigators.
Plasma C-Reactive Protein and Clinical Outcomes after Acute Ischemic Stroke: A Prospective Observational Study.

PLoS One. 2016;11(6):e0156790.

Nakamura A, Kuroda J, Ago T, Hata J, Matsuo R, Arakawa S, Kuwashiro T, Yasaka M, Okada Y, Kitazono T, Kamouchi M; Fukuoka Stroke Registry Investigators.
Causes of Ischemic Stroke in Patients with Non-Valvular Atrial Fibrillation.
Cerebrovasc Dis. 2016;42(3-4):196-204

2015年

Fukuda K, Kai H, Kamouchi M, Hata J, Ago T, Nakane H, Imaizumi T, Kitazono T; FSR Investigators.
Day-by-Day Blood Pressure Variability and Functional Outcome After Acute Ischemic Stroke: Fukuoka Stroke Registry.
Stroke. 2015 Jun 11. pii: STROKEAHA.115.009076. [Epub ahead of print]
脳梗塞急性期の血圧日内変動は、3カ月後の予後不良に関与していることが明らかとなりました。

Irie F, Kamouchi M, Hata J, Matsuo R, Wakisaka Y, Kuroda J, Ago T, Kitazono T; FSR Investigator
Sex differences in short-term outcomes after acute ischemic stroke: the fukuoka stroke registry.
Stroke. 2015 Feb;46(2):471-6.

2014年

Matsuo R, Kamouchi M, Fukuda H, Hata J, Wakisaka Y, Kuroda J, Ago T, Kitazono T; FSR Investigators.
Intravenous Thrombolysis with Recombinant Tissue Plasminogen Activator for Ischemic Stroke Patients over 80 Years Old: The Fukuoka Stroke Registry.
PLoS One. 2014 Oct 16;9(10):e110444.

Ogata T, Kamouchi M, Matsuo R, Hata J, Kuroda J, Ago T, Sugimori H, Inoue T, Kitazono T; Fukuoka Stroke Registry Investigators.
Gastrointestinal bleeding in acute ischemic stroke: recent trends from the Fukuoka Stroke Registry.
Cerebrovasc Dis Extra. 2014 Jul 22;4(2):156-64.

Kuwashiro T, Ago T, Kamouchi M, Matsuo R, Hata J, Kuroda J, Fukuda K, Sugimori H, Fukuhara M, Awano H, Isomura T, Suzuki K, Yasaka M, Okada Y, Kiyohara Y, Kitazono T.
Significance of plasma adiponectin for diagnosis, neurological severity and functional outcome in ischemic stroke - Research for Biomarkers in Ischemic Stroke (REBIOS).
Metabolism. 2014;14(4):1093-103

Wakisaka Y, Ago T, Kamouchi M, Kuroda J, Matsuo R, Hata J, Gotoh S, Isomura T, Awano H, Suzuki K, Fukuda K, Okada Y, Kiyohara Y, Ooboshi H, Kitazono T; REBIOS Investigators.
Plasma S100A12 is associated with functional outcome after
ischemic stroke: Research for Biomarkers in Ischemic Stroke.

J Neurol Sci. 2014;340:75-9.

Matsuo R, Ago T, Hata J, Kuroda J, Wakisaka Y, Sugimori H, Kitazono T, Kamouchi M; FSR Investigators.
Impact of the 1425G/A Polymorphism of PRKCH on the Recurrence of Ischemic Stroke: Fukuoka Stroke Registry.
J Stroke Cerebrovasc Dis. 2014; 23(6):1356-61
PRKCH遺伝子のSNP1425G/Aは日本人脳梗塞患者の再発には関連しない可能性が示されました.

Kiyohara T, Kamouchi M, Kumai Y, Ninomiya T, Hata J, Yoshimura S, Ago T, Okada Y, Kitazono T; for the FSR investigators.
ABCD3 and ABCD3-I Scores Are Superior to ABCD2 Score in the Prediction of Short- and Long-Term Risks of Stroke After Transient Ischemic Attack.
Stroke. 2014 Feb;45(2):418-25.
ABCD3またはABCD3-IスコアはABCD2スコアよりも一過性脳虚血発作発症後の短期,長期予後の予測に有用であることが示されました.

Matsuo R, Kamouchi M, Ago T, Hata J, Shono Y, Kuroda J, Wakisaka Y, Sugimori H, Kitazono T; FSR investigators.
Thrombolytic therapy with intravenous recombinant tissue plasminogen activator in Japanese older patients with acute ischemic stroke: Fukuoka Stroke Registry.
Geriatr Gerontol Int. 2014; 63(9):954-9
75歳以上の日本人高齢者において経静脈的血栓溶解療法は有効である可能性が示されました.

Ishitsuka K, Kamouchi M, Hata J, Fukuda K, Matsuo R, Kuroda J, Ago T, Kuwashiro T, Sugimori H, Nakane H, and Kitazono T
High blood pressure after acute ischemic stroke is associated with poor clinical outcomes: Fukuoka Stroke Registry
Hypertension 2014; 63(1):54-60
脳梗塞発症後の平均血圧が高値であると予後が不良であることが示されました.

2013年

Makihara N, Kamouchi M, Hata J, Matsuo R, Ago T, Kuroda J, Kuwashiro T, Sugimori H, Kitazono T; on behalf of the Fukuoka Stroke Registry Investigators.
Statins and the Risks of Stroke Recurrence and Death after Ischemic Stroke: The Fukuoka Stroke Registry
Atherosclerosis 2013; 231(2):211-5.
退院後のスタチン内服は脳梗塞再発または死亡のリスクを軽減する可能性が示されました.

Nakamura A, Ago T, Kamouchi M, Hata J, Matsuo R, Kuroda J, Kuwashiro T, Sugimori H, Kitazono T; on behalf of the Fukuoka Stroke Registry Investigators.
Intensity of Anticoagulation and Clinical Outcomes in Acute Cardioembolic Stroke: The Fukuoka Stroke Registry.
Stroke. 2013;44(11):3239-42.
ワルファリン投与中に発症した心原性脳塞栓患者においては、抗凝固療法の強度は臨床予後と相関することが示されました.

Tokami H, Ago T, Sugimori H, Kuroda J, Awano H, Suzuki K, Kiyohara Y, Kamouchi M, Kitazono T;REBIOS Investigators.
RANTES has a potential to play a neuroprotective role in an autocrine/paracrine manner after ischemic stroke.
Brain Res.2013 Jun 23;1517:122-32.Epub 2013 Apr 18
ケモカインRANTESは急性期脳梗塞において神経保護的に作用する可能性が示されました.

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